Challenges in ensuring global access to COVID‐19 vaccines: production, affordability, allocation, and deployment. Wouters OJ, Shadlen KC, Salcher‐Konrad M, et al. Perioperative SARS‐CoV‐2 infections increase mortality, pulmonary complications, and thromboembolic events: a Dutch, multicenter, matched‐cohort clinical study. Jonker PKC, van der Plas WY, Steinkamp PJ, et al. Journal of Clinical Oncology 2021 39: 66–78. Elective cancer surgery in COVID‐19‐free surgical pathways during the SARS‐CoV‐2 pandemic: an international, multicenter, comparative cohort study. Glasbey JC, Nepogodiev D, Simoes JFF, et al. Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS‐CoV‐2 infection: an international cohort study. Anaesthesia published by John Wiley & Sons Ltd on behalf of Association of Anaesthetists.ĬOVIDSurg Collaborative. Patients with ongoing symptoms ≥ 7 weeks from diagnosis may benefit from further delay.ĬOVID-19 SARS-CoV-2 delay surgery timing. Where possible, surgery should be delayed for at least 7 weeks following SARS-CoV-2 infection. After a ≥ 7 week delay in undertaking surgery following SARS-CoV-2 infection, patients with ongoing symptoms had a higher mortality than patients whose symptoms had resolved or who had been asymptomatic (6.0% (95%CI 3.2-8.7) vs. Surgery performed ≥ 7 weeks after SARS-CoV-2 diagnosis was associated with a similar mortality risk to baseline (odds ratio (95%CI) 1.5 (0.9-2.1)). In patients with a pre-operative SARS-CoV-2 diagnosis, mortality was increased in patients having surgery within 0-2 weeks, 3-4 weeks and 5-6 weeks of the diagnosis (odds ratio (95%CI) 4.1 (3.3-4.8), 3.9 (2.6-5.1) and 3.6 (2.0-5.2), respectively). Adjusted 30-day mortality in patients without SARS-CoV-2 infection was 1.5% (95%CI 1.4-1.5). Among 140,231 patients (116 countries), 3127 patients (2.2%) had a pre-operative SARS-CoV-2 diagnosis. Logistic regression models were used to calculate adjusted 30-day mortality rates stratified by time from diagnosis of SARS-CoV-2 infection to surgery. The primary outcome measure was 30-day postoperative mortality. Surgical patients with pre-operative SARS-CoV-2 infection were compared with those without previous SARS-CoV-2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October 2020.

The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS-CoV-2 infection. Peri-operative SARS-CoV-2 infection increases postoperative mortality.

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